Metabolomics analysis of human plasma reveals decreased production of trimethylamine N-oxide retards the progression of chronic kidney disease.
Da-Yong HuMing-Yu WuGuang-Qi ChenBing-Qing DengHai-Bo YuJian HuangYing LuoMeng-Yuan LiDa-Ke ZhaoJun Yan LiuPublished in: British journal of pharmacology (2022)
Our data show that decreased TMAO production could be a new strategy to attenuate the progression of renal injury in CKD.