Periosteum-inspired in situ CaP generated nanocomposite hydrogels with strong bone adhesion and superior stretchability for accelerated distraction osteogenesis.

Tengfei LouKai ChenQiyu LuoChangsheng LiuYuan YuanCunyi Fan

Published in: Biomaterials research (2022)

This periosteum-inspired nanocomposite hydrogel represents a mechanobiology approach for effectively restoring large bone defects through the dynamic DO process.

Keyphrases

bone mineral density
bone regeneration
drug delivery
reduced graphene oxide
hyaluronic acid
soft tissue
quantum dots
bone loss
tissue engineering
wound healing
carbon nanotubes
solid phase extraction
highly efficient
escherichia coli
biofilm formation
body composition
drug release