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Persistent Changes in Stress-Regulatory Genes in Pregnant Women or Children Exposed Prenatally to Alcohol.

Dipak K SarkarOmkaram GangisettyJeffrey R WozniakJudith K EckerleMichael K GeorgieffTatiana M ForoudLeah WetherillWladimir WerteleckiChristina D ChambersEdward RileyNatalya Zymak-ZakutnyaLyubov Yevtushok
Published in: Alcoholism, clinical and experimental research (2019)
These data suggest that PAE significantly elevates DNA methylation of POMC and PER2 and increases levels of stress hormones. Furthermore, these results suggest the possibility that measuring DNA methylation levels of PER2 and POMC in biological samples from pregnant women or from children may be useful for identification of a woman or a child with PAE.
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