Associations Between Blood Concentrations of Sex Hormones and Physical Function in Community-Dwelling Older Women: A Prospective Cohort Study.
Yuanyuan WangRakibul M IslamSultana Monira HussainJohn J McNeillSusan R DavisPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
Low endogenous concentrations of testosterone and dehydroepiandrosterone were associated the greatest likelihood of physical function decline in community-based women aged ≥70 years. Further studies are warranted to determine whether testosterone and dehydroepiandrosterone therapy prevent functional decline in this at-risk group using sensitive measures of muscle strength and performance.