Cannabidiol improves survival and behavioural co-morbidities of Dravet syndrome in mice.
Pabitra Hriday PatraEleni Serafeimidou-PouliouMichael BazelotBenjamin Jason WhalleyClaire Michelle WilliamsAlister James McNeishPublished in: British journal of pharmacology (2020)
We are the first to demonstrate a potential disease-modifying effect of cannabidiol in animal models of Dravet syndrome. Cannabidiol treatment reduced premature mortality and improved several behavioural co-morbidities in Dravet syndrome mice. These crucial findings may be translated into human therapy to address behavioural co-morbidities associated with Dravet syndrome.