The protective effect of betacellulin against acute pancreatitis is ERBB4 dependent.

Kathrin HedeggerFranziska StumpfHelmut BlumAlexander GrafRoland Michael SchmidMarina LesinaHana AlgülMarlon Roberto SchneiderMaik Dahlhoff

Published in: Journal of gastroenterology (2019)

These findings suggest that BTC derivates, as a drug, or the ERBB4 receptor, as a druggable target protein, could play an important role in modulating the course of AP and even prevent AP in humans.

Keyphrases

transcription factor
tyrosine kinase
binding protein
signaling pathway
protein protein
electronic health record