CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development.
Harinarayana AnkamreddyHeiyeun KooYoung Jae LeeJinwoong BokPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
CXCL12 plays an essential role in establishing the stirrup-shaped architecture of the stapes, possibly by maintaining the stapedial foramen and stapedial artery throughout development.
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