Apathy predicts rate of cognitive decline over 24 months in premanifest Huntington's disease.

S C AndrewsD R LangbehnD CraufurdA DurrB R LeavittR A RoosS J TabriziJulie C Stoutnull null

Published in: Psychological medicine (2020)

Our findings indicate that in premanifest HD, apathy is a harbinger for cognitive decline. In contrast, after motor onset, in early diagnosed HD, motor symptom severity more strongly predicts the rate of cognitive decline.

Keyphrases

cognitive decline
mild cognitive impairment
magnetic resonance