Increased Complement Activation in Systemic Sclerosis Patients with Skin and Lung Fibrosis.

Chiara PellicanoMarzia MiglionicoLaura RomaggioliAmalia ColalilloLorenzo VantaggioCecilia NapodanoCinzia CallàFrancesca GulliMariapaola Marino Umberto Basile Edoardo Rosato

Published in: Journal of personalized medicine (2022)

Our results show an increment of CH50 and serum C2 levels in SSc patients in comparison to HC; we retain that CH50 may represent a biomarker of disease severity and of skin and lung fibrosis in these patients.

Keyphrases

systemic sclerosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
interstitial lung disease
room temperature
soft tissue
patient reported
liver fibrosis