Determination of Voriconazole Plasma Concentration by HPLC Technique and Evaluating Its Association with Clinical Outcome and Adverse Effects in Patients with Invasive Aspergillosis.

Sahar Yousefian Farzaneh Dastan Majid Marjani Payam Tabarsi Saghar Barati Nahid Shahsavari Atefeh Hajiagha Bozorgi

Published in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (2021)

TDM of VRZ plays an important role in better evaluation of efficacy and toxicity during treatment. Therefore, determination of the drug level may be of clinical significance.

Keyphrases

solid phase extraction
molecularly imprinted
high performance liquid chromatography

ms ms
simultaneous determination
tandem mass spectrometry

oxidative stress
mass spectrometry
emergency department

adverse drug
electronic health record