SARS-CoV-2 clade dynamics and their associations with hospitalisations during the first two years of the COVID-19 pandemic.
Taavi PällAare AbroiRadko AviHeiki NiglasArina ShablinskajaMerit PauskarEne-Ly JõgedaHiie SoeorgEveli KallasAndrio LahesaareKai TruusaluDagmar HoidmetsOlga SadikovaKaspar RatnikHanna SeppLiidia DotsenkoJevgenia EpšteinHeleene SuijaKatrin KaarnaSteven SmitLili MilaniMait MetspaluOtt Eric OopkaupIvar KoppelErik JaanisoIvan KuzminHeleri InnoUku RaudvereMari-Anne HärmaPaul NaaberTuuli ReisbergHedi PetersonUlvi Gerst TalasIrja LutsarKristi HuikPublished in: PloS one (2024)
COVID-19 disease waves in Estonia were driven by the Alpha, Delta, and Omicron clades. Omicron clades were associated with a substantially lower hospitalisation probability than pre-Omicron clades. The protective effect of vaccination in reducing hospitalisation likelihood was independent of the involved clade.