Deep sequencing analysis of serum hepatitis B virus-RNA during nucleot(s)ide analogue therapy.

Shuya MatsudaShinya MaekawaYasuyuki KomiyamaNatsuko NakakukiMasaru MuraokaYuichiro SuzukiMitsuaki SatoAkihisa TatsumiMika MiuraFumitake AmemiyaHiroko ShindoShinichi TakanoMitsuharu FukasawaTatsuya YamaguchiYasuhiro NakayamaTaisuke InoueTadashi SatoAtsuya YamashitaKohji MoriishiNobuyuki Enomoto

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2021)

Serum HBV-RNA could reflect the transcriptional activity of covalently closed circular DNA and hepatitis B core-related antigen. The dynamics of HBV-RNA could help understanding of the turnover process of HBV covalently closed circular DNA in the liver.

Keyphrases

hepatitis b virus
nucleic acid
liver failure
circulating tumor
cell free
single molecule
gene expression
single cell
bone mineral density
stem cells