Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis.

Dongmei HuShaojie HuangYi DingXian ZhaoWei ZhangHaixia ChenJing-Wen Wang

Published in: The Journal of pharmacy and pharmacology (2022)

Specnuezhenide reduced CCl4-induced liver injury in mice by inhibiting oxidative stress via activation of Nrf2 signalling and decreasing hepatocyte apoptosis.

Keyphrases

oxidative stress
liver injury
drug induced
diabetic rats
dna damage
ischemia reperfusion injury
induced apoptosis
high fat diet induced
endoplasmic reticulum stress
cell cycle arrest
cell death
signaling pathway
cell proliferation
liver fibrosis
adipose tissue
heat stress