In-vitro evaluation of a ciprofloxacin and azithromycin sinus stent for Pseudomonas aeruginosa biofilms.
Dong-Jin LimDaniel SkinnerJohn MclemoreNick RiversJeffrey Brent ElderMark AllenConnor KochJohn WestShaoyan ZhangHarrison M ThompsonJustin P McCormickJessica W GraysonDo-Yeon ChoBradford A WoodworthPublished in: International forum of allergy & rhinology (2019)
The CASS maintains a uniform coating and sustained delivery of ciprofloxacin and azithromycin, providing anti-biofilm activities against P aeruginosa. Further studies evaluating the efficacy of CASS in a preclinical model are planned.