In vivo pharmacodynamic study of contezolid acefosamil, a prodrug of contezolid for oral and intravenous administration.

Xiu-Kun WangJie YuChun-Yang XieXin-Xin HuTong-Ying NieXue LiPeng-He WangGuo-Qing LiHong YuanXin-Yi YangCong-Ran LiXue-Fu You

Published in: The Journal of antimicrobial chemotherapy (2023)

The high aqueous solubility and great efficacy of contezolid acefosamil support its clinical development as an injectable and oral antibiotic suitable for serious Gram-positive infections.

Keyphrases

gram negative
drug release
drug delivery
low dose
hyaluronic acid