Molecular epidemiology and mechanisms of tigecycline resistance in carbapenem-resistant Klebsiella pneumoniae isolates.

Yumi Park Qute ChoiGye Cheol KwonSun Hoe Koo

Published in: Journal of clinical laboratory analysis (2020)

We found that the activated MarA-induced overexpression of AcrAB efflux pump plays an important role in the emergence of tigecycline resistance in CRKP isolates.

Keyphrases

klebsiella pneumoniae
multidrug resistant
escherichia coli
acinetobacter baumannii
genetic diversity
high glucose
diabetic rats
drug resistant
transcription factor
oxidative stress
pseudomonas aeruginosa
endothelial cells