Efficacy and Durability of Dolutegravir- or Darunavir-Based Regimens in ART-Naïve AIDS- or Late-Presenting HIV-Infected Patients.

Massimiliano FabbianiMelissa MasiniBarbara RossettiArturo CicculloVanni BorghiFilippo LagiAmedeo Ferdinando CapettiManuela ColafigliFrancesca PanzaGianmaria BaldinCristina MussiniGaetana Sterrantino Damiano Farinacci Francesca Montagnani Mario TumbarelloSimona Di Giambenedetto

Published in: Viruses (2023)

Dolutegravir and darunavir showed similar efficacy in AIDS- and late-presenting patients. A higher risk of TD due to CNS toxicity was observed with dolutegravir, and a higher probability of treatment simplification with darunavir.

Keyphrases

hiv infected patients
antiretroviral therapy
hiv infected
end stage renal disease
newly diagnosed
ejection fraction
oxidative stress
prognostic factors
blood brain barrier
patient reported outcomes
patient reported