Superiority of intensity-modulated radiation therapy in nasopharyngeal carcinoma with skull-base invasion.
Shufang LiaoYuan XieYi FengYuanyuan ZhouYufei PanJinfang FanJinglin MiXiaoli QinDacheng YaoWei JiangPublished in: Journal of cancer research and clinical oncology (2019)
IMRT significantly improved patient survival compared with 2DRT in NPC patients with severe skull-base invasion, but a similar survival rate was noted in mild invasion patients. Chemotherapy can improve survival in NPC patients with severe invasion. Among the two therapies, IMRT significantly decreased therapy-related toxicity.