MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment data.

Jingting XuShimeng LiuPing YinSerdar BulunYang Dai

Published in: BMC bioinformatics (2018)

The MeDEStrand tool can be used to infer whole-genome absolute DNA methylation levels at the same cost of enrichment-based methods with adequate accuracy and resolution. R package MeDEStrand and its tutorial is freely available for download at https://github.com/jxu1234/MeDEStrand.git .

Keyphrases

genome wide
dna methylation
single molecule
gene expression
copy number
circulating tumor
big data
machine learning
artificial intelligence
deep learning