Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock: A Systematic Review and Meta-Analysis.

Mohd H Abdul-AzizNaomi E HammondStephen J BrettMenino O CottaJan J De WaeleAnthony DevauxGian Luca Di TannaJoel M DulhuntyHatem ElkadyLars ErikssonM Shahnaz HasanAyesha Bibi KhanJeffrey LipmanXiaoqiu LiuGiacomo MontiJohn MyburghEmmanuel NovyShahed OmarDorrilyn RajbhandariClaire RogerFredrik SjövallIrene ZaghiAlberto ZangrilloAnthony DelaneyJason A Roberts

Published in: JAMA (2024)

PROSPERO Identifier: CRD42023399434.

Keyphrases

septic shock
high intensity

gram negative

multidrug resistant

intensive care unit