Lack of RBC transfusion independence by Day 30 following allogeneic hematopoietic stem cell transplant strongly predicts inferior survival and high non-relapse mortality in acute myeloid leukemia patients.
Shan YuanDongyun YangRyotaro NakamuraMonzr M Al MalkiAmandeep SalhotraMichelle AfkhamiShirong WangPublished in: Transfusion (2024)
Prolonged RBC dependence predicted worse survival and NRM rates, but not increased relapse. Posttransplant surveillance of such patients should be adjusted with more attention to non-relapse complications.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- hematopoietic stem cell
- free survival
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- public health
- risk factors
- type diabetes
- stem cell transplantation
- cardiovascular disease
- cardiovascular events
- coronary artery disease
- cardiac surgery
- working memory