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Reconstruction of Acinetobacter johnsonii ICE_NC genome using hybrid de novo genome assemblies and identification of the 12α-hydroxysteroid dehydrogenase gene.

Nicoletta FavaleStefania CostaChiara ScapoliAlberto CarrieriSilvia SabbioniElena TamburiniAndrea BenazzoGiovanni Bernacchia
Published in: Journal of applied microbiology (2022)
At present, this is the first report on the characterization of a 12α-HSDH gene in an A. johnsonii strain able to biotransform cholic acid into ursodeoxycholic acid, a promising therapeutic agent for several diseases.
Keyphrases
  • genome wide
  • copy number
  • dna methylation
  • genome wide identification
  • cystic fibrosis
  • pseudomonas aeruginosa