Integrating farm and air pollution studies in search for immunoregulatory mechanisms operating in protective and high-risk environments.
Maria-Viola MartikainenTeemu J RönkköBianca SchaubMartin TäubelCheng GuGary Wing Kin WongJing LiJuha PekkanenMika KomppulaMaija-Riitta HirvonenPasi I JalavaMarjut RoponenPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)
Our study demonstrates the significance of using the same research framework when disentangling shared and distinctive immune pathways operating in different environments. Observed stimulatory effects of farm dust and inhibitory effects of PM could shape responses towards respiratory pathogens and allergens, and partly explain differences in asthma prevalence between studied environments.