Abnormal Peripheral Neutrophil Transcriptome in Newly Diagnosed Type 2 Diabetes Patients.

Qiuqiu Lin Wenzhi Zhou Yanfei WangJuan HuangXiaoyan HuiZhi-Guang Zhou Yang Xiao

Published in: Journal of diabetes research (2020)

Our study reveals an abnormal activation of circulating neutrophils at the transcriptome level in type 2 diabetes patients. These findings suggest a potential involvement of neutrophil dysfunction in the pathologic process of type 2 diabetes and provide insight into potential therapeutic targets for type 2 diabetes.

Keyphrases

type diabetes
newly diagnosed
end stage renal disease
ejection fraction
chronic kidney disease
glycemic control
cardiovascular disease
gene expression
insulin resistance
peritoneal dialysis
rna seq
metabolic syndrome
radiation therapy
skeletal muscle
neoadjuvant chemotherapy
patient reported