Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
Fei XueJianmin YangJing ChengWenhai SuiCheng ChengHongxuan LiMeng ZhangJie ZhangXing Li XuJing MaLin LuJinfeng XuMeng ZhangYun ZhangCheng ZhangPublished in: British journal of pharmacology (2020)
Ang-(1-7) treatment attenuated Ang II-induced AAA via inhibiting vascular inflammation, extracellular matrix degradation, and SMC apoptosis. Ang-(1-7) may provide a novel and promising approach to the prevention and treatment of AAA.