Haptoglobin is associated with increased early perihematoma edema progression in spontaneous intracranial hemorrhage.
Michael R HalsteadW Andrew MouldKevin N ShethJonathan RosandRichard ThompsonAndrew LevyDaniel F HanleyJoshua N GoldsteinPaul NyquistPublished in: International journal of stroke : official journal of the International Stroke Society (2020)
Haptoglobin phenotype is associated with early change in perihematomal volume. Hp 1-1 phenotype had significantly increased mean rate of early change in perihematomal volume within the first 96 h, suggesting that haptoglobin phenotype may be a key player in understanding the multiphasic progression of perihematomal volume in spontaneous intracerebral hemorrhage. A larger prospective observational study is warranted.
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