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A prospective randomized open-label trial on the comparative effects of 6% hydroxyethyl starch 130/0.4 versus polyionic isotonic crystalloids on coagulation parameters in dogs with spontaneous hemoperitoneum.

Claudia IannucciDaniel DirkmannJudith HowardKatja N Adamik
Published in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) (2020)
Compared to a 3-fold volume of CRYS, administration of HES was associated with impairment in ROTEM parameters in dogs with SHP, but no evidence of hyperfibrinolysis was detected.
Keyphrases
  • open label
  • phase iii
  • phase ii
  • clinical trial
  • study protocol
  • phase ii study
  • radiation therapy
  • double blind