A Multicenter Study of the Validity and Reliability of Responses to Hand Cold Challenge as Measured by Laser Speckle Contrast Imaging and Thermography: Outcome Measures for Systemic Sclerosis-Related Raynaud's Phenomenon.
Jack D WilkinsonSarah A LeggettElizabeth J MarjanovicTonia L MooreJohn AllenMarina E AndersonJason BrittonMaya H BuchFrancesco Del GaldoChristopher P DentonGraham DinsdaleBridgett GriffithsFrances HallKevin HowellAudrey MacDonaldNeil J McHughJoanne B ManningJohn D PaulingChristopher RobertsJacqueline A ShipleyAriane L HerrickAndrea K MurrayPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2018)
This is the first multicenter study to examine the reliability and validity of cold challenge using LSCI and thermography in patients with SSc-related RP. LSCI and thermography both demonstrated good potential as outcome measures. LSCI, standard thermography, and mobile thermography had very high convergent validity.