Antifungal mechanism of action of Schinus lentiscifolius Marchand essential oil and its synergistic effect in vitro with terbinafine and ciclopirox against dermatophytes.

Leticia J DanielliBruna PippiJonathaline A DuarteAna J MacielWilliam LopesMichel M MachadoLuis Flávio S OliveiraMarilene H VainsteinMário L TeixeiraSérgio A L BordignonAlexandre M FuentefriaMiriam A Apel

Published in: The Journal of pharmacy and pharmacology (2018)

Schinus lentiscifolius essential oil acted as a chemosensitizer of the fungal cell to the drug, resulting in an improvement in the antifungal effect. Therefore, this combination can be considered as an alternative for the topical treatment of dermatophytosis.

Keyphrases

essential oil
candida albicans
single cell
cell therapy
stem cells
emergency department
combination therapy
bone marrow
drug induced