Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture.

William SwiftJeffrey A BairWanxue ChenMichael LiSole LieDayu LiMenglu YangMarie A ShatosRobin R HodgesMiriam KolkoTor P UtheimWendell ScottDarlene A Dartt

Published in: BMJ open ophthalmology (2020)

We conclude that PI, which is commonly used prior to ocular surgeries, is detrimental to human conjunctival stratified squamous cells, goblet cells and fibroblasts in culture.

Keyphrases

induced apoptosis
cell cycle arrest
endothelial cells
endoplasmic reticulum stress
computed tomography
magnetic resonance
signaling pathway
high grade