A new mouse model to study restoration of interleukin-6 (IL-6) expression in a Cre-dependent manner: microglial IL-6 regulation of experimental autoimmune encephalomyelitis.
Paula SanchisOlaya Fernández-GayolGemma ComesKevin AguilarAnna EscrigMercedes GiraltRichard D PalmiterJuan HidalgoPublished in: Journal of neuroinflammation (2020)
IL6-DIO-KO mouse is an excellent model to understand in detail the role of specific cellular sources of IL-6 within a recovery-of-function paradigm in EAE.