The Proton Resonance Enhancement for CEST imaging and Shift Exchange (PRECISE) family of RF pulse shapes for Chemical Exchange Saturation Transfer MRI.

Zinia MohantaJulia StabinskaAssaf A GiladPeter B BarkerMichael T McMahon

Published in: bioRxiv : the preprint server for biology (2024)

A new 100 msec pulse was developed based on gradient ascent optimizations which produced better contrast compared to standard Gaussian and Fermi pulses in phantoms. This shape also showed a substantial improvement for CEST MRI pH mapping in live mice over the Gaussian shape and appears promising for a wide range of CEST applications.

Keyphrases

contrast enhanced
high resolution
magnetic resonance imaging
blood pressure
diffusion weighted imaging
magnetic resonance
computed tomography
high fat diet induced
energy transfer
high density
type diabetes
electron transfer
photodynamic therapy
fluorescence imaging
quantum dots