Efficacy and Safety of Two-Drug Regimens with Dolutegravir plus Rilpivirine or Lamivudine in HIV-1 Virologically Suppressed People Living with HIV.

Carlos Dueñas-Gutiérrez Luis Buzón Martín Roberto Pedrero-ToméJosé A IribarrenIgnacio De Los Santos Sara De la Fuente Guillermo PousadaMiguel Angel MoranEstela MorenoEva FerreiraJulia GómezJesús Troya García

Published in: Viruses (2023)

We conclude that DTG-based 2DRs (combined with 3TC or RPV) in clinical practice were effective and safe as a switching strategy, with a low VF and high viral suppression rates. Both regimens were well tolerated, and ADR rates were low, including neurotoxicity and induced treatment discontinuations.

Keyphrases

hiv infected patients
antiretroviral therapy
hiv infected
hiv positive
clinical practice
human immunodeficiency virus
hiv aids
adverse drug
hepatitis c virus
sars cov
drug induced
hiv testing
diabetic rats
emergency department
endothelial cells
combination therapy
replacement therapy