A reliable transcriptomic risk-score applicable to formalin-fixed paraffin-embedded biopsies improves outcome prediction in localized prostate cancer.

Michael RadeMarkus KreuzAngelika BorkowetzUlrich SommerConny BlumertSusanne FüsselCatharina BertramDennis LöfflerDominik J OttoLivia A WöllerCarolin SchimmelpfennigUlrike KöhlAnn-Cathrin GottschlingPia HönscheidGustavo B BarettonManfred WirthChristian ThomasFriedemann HornKristin Reiche

Published in: Molecular medicine (Cambridge, Mass.) (2024)

We developed a prognostic gene-expression signature for PCa that can be applied to FFPE biopsies and may be suitable to support clinical decision-making.

Keyphrases

prostate cancer
gene expression
decision making
radical prostatectomy
dna methylation
ultrasound guided
single cell
rna seq