Cognitive outcomes after multimodal treatment in adult glioma patients: A meta-analysis.
Laurien De RoeckR Céline GillebertRobbie C M van AertAmber VanmeenenMartin KleinMartin J B TaphoornKarin GehringMaarten LambrechtCharlotte SleursPublished in: Neuro-oncology (2023)
Cognitive performance of glioma patients one year after treatment is significantly lower compared to the norm, with specific tests potentially being more sensitive. Cognitive decline over time occurs as well, but can easily be overlooked in longitudinal designs due to practice effects (as a result of interval testing). It is warranted to sufficiently correct for practice effects in future longitudinal trials.