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The impact of chronic kidney disease Stages 3-5 on pregnancy outcomes.

Kate WilesPhilip WebsterPaul T SeedKaty Bennett-RichardsKate BramhamNigel BrunskillSue CarrMatt HallRehan KhanCatherine Nelson-PiercyLouise M WebsterLucy C ChappellLiz Lightstone
Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2022)
Contemporary pregnancies in women with CKD Stages 3-5 are complicated by preterm delivery, low birthweight and loss of maternal renal function. Chronic hypertension, pre- or early pregnancy proteinuria and a gestational fall in serum creatinine of <10% of pre-pregnancy values are more important predictors of adverse obstetric and renal outcome than CKD Stages 3-5. Pregnancy in women with CKD Stages 3-5 advances the need for dialysis or transplantation by 2.5 years.
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