Baicalin Exerts a Protective Effect in Diabetic Nephropathy by Repressing Inflammation and Oxidative Stress Through the SphK1/S1P/NF-κB Signaling Pathway.
Gaofei RenPengfei JiaoYushan YanXiaojun MaGui-Jun QinPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2023)
Our study strongly suggests that BA protects against DN via ameliorating inflammation, oxidative stress and apoptosis through the SphK1/S1P/NF-κB pathway. This study provides a novel insight into the therapeutic effects of BA in DN.