Multi-compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice.

Sarah A PötgensMorgane M ThibautNicolas JoudiouMartina SboarinaAudrey M Neyrinck Patrice D CaniSandrine P ClausNathalie M Delzenne Laure B Bindels

Published in: Journal of cachexia, sarcopenia and muscle (2021)

Our work highlights new metabolic pathways potentially involved in cancer cachexia and further supports the interest of exploring the gut microbiota composition and activity, as well as intestinal transit, in cancer patients with and without cachexia.

Keyphrases

papillary thyroid
squamous cell
mass spectrometry
childhood cancer
lymph node metastasis
squamous cell carcinoma
gene expression
young adults
single cell