Myricitrin versus EGCG in the treatment of obesity: target mining and molecular mechanism exploring based on network pharmacology.

Peipei YinJiangping HuangKang YangChuang DengLingguang Yang

Published in: Current pharmaceutical design (2023)

The present research integrated network pharmacology and bioinformatics approach to reveal the key targets of Myricitrin and EGCG against obesity. The results provided novel insights into the molecular mechanism of Myricitrin and EGCG in obesity prevention and treatment and laid the foundations for the exploitation of flavonoid-containing herbal resources.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
type diabetes
weight gain
high fat diet induced
gene expression
genome wide
skeletal muscle
combination therapy
dna methylation
body mass index
replacement therapy