Predictors of acute ischemic cerebral lesions in immune-mediated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.
Lisa NeumanAdrien JosephRaïda BouzidMickael LescroartEric MariotteStéphane EderhySophie TuffetJean-Luc BaudelYgal BenhamouLionel GalicierSteven GrangéFrançois ProvôtAntoine NeelFrédéric PèneYahsou DelmasClaire PresnePascale PoullinAlain WynckelPierre PerezChristelle BarbetJean-Michel HalimiValérie ChateletJean-Michel RebibouMario Ojeda-UribeCécile VigneauLaurent MesnardAgnès VeyradierElie AzoulayPaul CoppoHugues Chabriatnull nullPublished in: Journal of neurology (2023)
At the acute phase of iTTP or HUS, both symptomatic and covert ischemic lesions are detected in one third of cases on MRI. Diagnosis of iTTP and the presence of old infarcts on MRI are associated with the occurrence of such acute lesions as well as increased blood pulse pressure, that may represent a potential target to further improve the therapeutic management of these conditions.
Keyphrases
- liver failure
- respiratory failure
- contrast enhanced
- magnetic resonance imaging
- cerebral ischemia
- aortic dissection
- drug induced
- risk assessment
- diffusion weighted imaging
- blood pressure
- ischemia reperfusion injury
- subarachnoid hemorrhage
- computed tomography
- brain injury
- human health
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome