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Loss of function polymorphisms in SLCO1B1 (c.521T>C, rs4149056) and ABCG2 (c.421C>A, rs2231142) genes are associated with adverse events of rosuvastatin: a case-control study.

Iveta MerćepIvana RadmanVladimir TrkuljaTamara BožinaLivija ŠimičevićEma BudimirLana GanociNada Božina
Published in: European journal of clinical pharmacology (2021)
Loss of function polymorphisms in SLCO1B1 c.521T>C and ABCG2 c.421C>A genes are associated with the presence of rosuvastatin related myotoxicity and/or hepatotoxicity.
Keyphrases
  • genome wide
  • bioinformatics analysis
  • genome wide identification
  • drug induced
  • gene expression
  • genome wide analysis
  • cancer stem cells