PRL -1149T allele (rs1341239) is associated with decreased risk of rheumatoid arthritis in population from southern Mexico: analysis of mRNA expression and PRL serum levels.
J E Navarro-ZarzaJ F Muñoz-ValleC J Baños-HernándezI Parra-RojasZ Reyes-CastilloH Rangel-VillalobosJorge Hernández-BelloPublished in: Clinical rheumatology (2019)
• PRL -1149T allele is a marker of decreased RA susceptibility in population from southern Mexico. • PRL -1149TT genotype is associated with low PRL mRNA expression. • RA patients have higher mRNA expression and soluble levels of PRL than healthy subjects. • PRL serum levels are higher in those RA patients with < 2 years of disease evolution.