Systematic review: predicting and optimising response to anti-TNF therapy in Crohn's disease - algorithm for practical management.
Nik Sheng DingA HartP De CruzPublished in: Alimentary pharmacology & therapeutics (2015)
Nonresponse or loss of response to anti-TNF occurs commonly in Crohn's disease. Clinical algorithms utilising therapeutic drug monitoring may establish the mechanisms for treatment failure and help guide the subsequent therapeutic approach.