Characterization and functionality of two members of the SPFH protein superfamily, prohibitin 1 and 2 in Leishmania major.
Teresa Cruz-BustosAna Karina Ibarrola-VannucciIsabel Díaz-LozanoJosé Luis RamírezAntonio OsunaPublished in: Parasites & vectors (2018)
Here, we propose that PHBs may help to protect membranes and DNA against superoxide ions, thus enhancing the survival capacity of the protozoan by controlling the ROS within the phagosome of the macrophages where the parasite multiplies.
Keyphrases
- circulating tumor
- cell death
- dna damage
- cell free
- hydrogen peroxide
- single molecule
- quantum dots
- plasmodium falciparum
- reactive oxygen species
- protein protein
- toxoplasma gondii
- free survival
- amino acid
- trypanosoma cruzi
- binding protein
- nucleic acid
- oxidative stress
- genome wide identification
- circulating tumor cells
- transcription factor