HtrA-mediated E-cadherin cleavage is limited to DegP and DegQ homologs expressed by gram-negative pathogens.
Carmen M AbfalterMaria SchubertCamilla GötzThomas P SchmidtGernot PosseltSilja WesslerPublished in: Cell communication and signaling : CCS (2016)
These data indicate that E-cadherin cleavage is confined to HtrA/DegP and DegQ proteins representing an important prevalent step in bacterial pathogenesis.