Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.

Nghiem B Ha Srilakshmi SeetharamanDorothea S KentFrederick YaoAmy M Shui Chiung-Yu Huang Jeremy D Walston Jennifer C Lai

Published in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society (2023)

These biomarkers represent inflammatory, musculoskeletal, and endocrine/metabolic systems, reflecting the multiple physiologic derangements observed in frailty. These data lay the foundation for confirmatory work and development of a laboratory frailty index for patients with cirrhosis to improve diagnosis and prognostication.

Keyphrases

community dwelling
oxidative stress
electronic health record
big data
amino acid
machine learning
protein protein
artificial intelligence
deep learning