PD-L1 expression in non-small cell lung carcinoma: Comparison among cytology, small biopsy, and surgical resection specimens.
Jonas J HeymannWilliam A BulmanDavid SwinarskiCarlos A PaganJohn P CrapanzanoMehrvash HaghighiLadan FazlollahiMark B StooplerJoshua R SonettAdrian G SacherCatherine A ShuNaiyer A RizviAnjali SaqiPublished in: Cancer cytopathology (2017)
Quantification of PD-L1 expression is feasible on cytology specimens, and the results are comparable to those obtained from surgical resection and small biopsy specimens, including in matched specimens and using a single predictive IHC marker. Future studies will be necessary to determine the comparative value of other antibodies and their ability to predict response to immunotherapy. Cancer Cytopathol 2017;125:896-907. © 2017 American Cancer Society.