Targeted metabolomic analysis of early-trimester serum identifies potential mechanisms for late-onset preeclampsia.

Chihiro OkoshiHyo KyozukaTakahiro OmotoToma FukudaTsuyoshi MurataShun YasudaHirotaka IsogamiMiho Okutsu-OnoAkiko SatoKoichi HashimotoHidekazu NishigoriKeiya Fujimori

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2024)

During early pregnancy, glucosamine and serotonin levels in maternal serum may serve as early biomarkers for Lo-PE. As part of preconception care, pre-pregnancy dietary habits and mental health could potentially prevent Lo-PE onset.

Keyphrases

late onset
pregnancy outcomes
early onset
mental health
preterm birth
healthcare
pregnant women
palliative care
birth weight
pain management
physical activity
climate change