Extending the Contacts Breaks the Flow.
Amado Carreras-SuredaChristopher HenryNicolas DemaurexPublished in: Contact (Thousand Oaks (Ventura County, Calif.)) (2023)
In this news and views, we discuss our recent publication where we described how ER-PM membrane contact sites (MCS) are modulated during store operated calcium entry (SOCE). We also examine why enforcing ER-PM MCS by tethering proteins does not not enhance, but rather inhibits SOCE.