An In Vitro Verification of the Effects of Paeoniflorin on Lipopolysaccharide-Exposed Microglia.
Qiliang ChenYaojun LiuYuanyuan ZhangXinyu JiangYuqin ZhangTetsuya AsakawaPublished in: Evidence-based complementary and alternative medicine : eCAM (2020)
We provided evidence obtained in vitro concerning the neuroprotective effects of PF via suppressing activation of microglia, which might be associated with the NF-κB signaling pathway. These findings contribute to obtaining a deeper understanding of PF, a potential new treatment for brain injuries.
Keyphrases
- signaling pathway
- inflammatory response
- pi k akt
- lps induced
- neuropathic pain
- induced apoptosis
- epithelial mesenchymal transition
- cerebral ischemia
- toll like receptor
- white matter
- human health
- combination therapy
- nuclear factor
- immune response
- cell proliferation
- climate change
- risk assessment
- subarachnoid hemorrhage
- brain injury